Lyme-Aid Disease and Pets Information for Scientists and Veterinary Professionals

Lyme disease has been reported in dogs in all 48 contiguous states and, in endemic areas, 41% or more of dogs have been reported to be infected.1,2 Pets experience symptoms similar to humans when infected with Lyme disease, including: Fever, swelling of the joins, pain, loss of appetite and fatigue.3 There is a vaccine available for dogs, however, the efficacy is variable at best, with some reported to be only 50% efficacious.2 Moreover, there are safety concerns associated with vaccination including anaphylaxis and "post-vaccinal Lyme-like syndrome".4

  1. Levy, S.A. 2001. Use of a C6 ELISA test to evaluate the efficacy of a whole-cell bacterin for the prevention of naturally transmitted canine Borrelia burgdorferi infection. Vet Ther. 2002:3(4):420-424.
  2. Straubinger RK, Dharma Rao T, Davidson E, Summers BA, Jacobson RH, Frey AB. Protection against tick-transmitted Lyme disease in dogs vaccinated with a multiantigenic vaccine. Vaccine. 20:181-193.
  3. Greene, C.E., Straubinger, R.K. 2006. Borreliosis. In:Greene CE, ed. Infectious Diseases of the Dog and Cat. 3rd ed. St Louis, Missouri, Saunders Elsevier, p. 417-435.
  4. Klingborg, D.J., Hustead, D.R., Curry-Galvin, E.A., et al. 2002. AVMA council on biologic and therapeutic agents' report on cat and dog vaccines. JAVMA 221:1401-1407.